(KO Validated) EGFR Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-63241-60, E-AB-63241-120, E-AB-63241-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: EGFR
Target Synonym: EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA
Research Areas: Cancer, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P00533
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human EGFR (NP_005219.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000
Calculated MW: 44kDa/69kDa/77kDa/134kDa
Observed MW: 175kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only