ACP6 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-11367-60, E-AB-11367-120, E-AB-11367-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: ACP6
Target Synonym: Acid phosphatase 6; Acid phosphatase 6; lysophosphatidic; Acid phosphatase like 1; Acid phosphatase like protein 1; Acid phosphatase-like protein 1; ACP6; ACPL1; LPAP; Lysophosphatidic acid phosphatase 6; Lysophosphatidic acid phosphatase type 6; Lysophosphatidic acid phosphatase type 6 precursor; lysophosphatidic; PACPL1; PPA6
Research Areas: Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9NPH0
Background: Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Concentration: 0.2 mg/mL
Immunogen: Recombinant protein of human ACP6
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only