CaMK2 (Phospho-Thr286) Rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES17871-50, ES17871-100
Citations, Manuals and MSDS Available upon request.
Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca (2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],
Alternate Name: Calcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta; CaMK-II subunit delta; EC 2.7.11.17)
Source: Rabbit
Applications: WB; ELISA
Dilution: WB 1:500-2000, ELISA (peptide)1:5000-20000
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 54kD
Human Gene ID: 817
Human SWISS Prot NO: Q9UQM7/Q13557
Subcellular Location: Cell junction, synapse. Cell junction, synapse, postsynaptic density. Cell projection, dendritic spine. Cell projection, dendrite. Postsynaptic lipid rafts.
Research Use Only