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CRISP3 Polyclonal Antibody - E-AB-14895

CRISP3 Polyclonal Antibody - E-AB-14895

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CRISP3 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-14895-60, E-AB-14895-120, E-AB-14895-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CRISP3

Target Synonym: Aeg 2; Aeg2; CRIS3; CRISP 3; CRISP-3; Crisp3; CRS 3; CRS3; Cysteine rich secretory protein 3; Cysteine-rich secretory protein 3; dJ442L6.3; MGC126588; OTTHUMP00000016590; OTTHUMP00000039911; SGP 28; SGP28; SGP28 protein; Specific granule protein (28 kDa); Specific granule protein of 28 kDa

Research Areas: Cancer

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P54108

Background: Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. AEG is a sperm surface protein involved in the fusion of egg and sperm. Although CRISP-1 (also designated AEG-like protein, ARP, cysteine-rich secretory protein-1 or AEG-related protein) is not the ortholog of rodent AEG, it resembles AEG in that it is an epididymal secretory glycoprotein that binds to the postacrosomal region of the sperm head. CRISP-1 coats the postacrosomal region of sperm heads as they pass through the epididymis. CRISP-1 is found in all regions of the epididymis, ductus deferens, seminal plasma and sperm. CRISP-3 is expressed in pancreas and prostate tissues and, along with CRISP-1, is expressed in saliva.

Concentration: 0.3 mg/mL

Immunogen: Recombinant protein of human CRISP3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only