IKappaB-Beta Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP04677-20, BT-AP04677-50, BT-AP04677-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by NFKBIB belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Research Areas: Signal Transduction
Target Protein: NFKBIB
Applications: WB, ELISA
Reactivity: Human, Mouse
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: IkappaB-beta Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 37771
UniProt Accession: Human: Q15653; Mouse: Q60778
Synonyms: NFKBIB; IKBB; TRIP9; NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9
GeneID: Human: 4793; Mouse: 18036
Research Use Only