ILT-3 Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP04526-20, BT-AP04526-50, BT-AP04526-100
Citations, Manuals and MSDS Available upon request.
Background: LILRB4 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. The leukocyte immunoglobulin like receptor B4 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Areas: Immunology
Target Protein: LILRB4
Applications: IF, ELISA
Reactivity: Human
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: ILT-3 Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 49298
UniProt Accession: Human: Q8NHJ6; Mouse: Q64281
Synonyms: LILRB4; ILT3; LIR5; Leukocyte immunoglobulin-like receptor subfamily B member 4; CD85 antigen-like family member K; Immunoglobulin-like transcript 3; ILT-3; Leukocyte immunoglobulin-like receptor 5; L
GeneID: Human: 11006
Research Use Only