IRAK-M Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP04621-20, BT-AP04621-50, BT-AP04621-100
Citations, Manuals and MSDS Available upon request.
Background: IRAK3 encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. Interleukin-1 receptor-associated kinase 3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
Research Areas: Immunology
Target Protein: IRAK3
Applications: WB, IHC-p, IF, ELISA
Reactivity: Human
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: IRAK-M Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 67753
UniProt Accession: Human: Q9Y616; Mouse: Q8K4B2
Synonyms: IRAK3; Interleukin-1 receptor-associated kinase 3; IRAK-3; IL-1 receptor-associated kinase M; IRAK-M
GeneID: Human: 11213
Research Use Only