IRE1Alpha/Beta Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP04622-20, BT-AP04622-50, BT-AP04622-100
Citations, Manuals and MSDS Available upon request.
Background: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.
Research Areas: Others
Target Protein: ERN2
Applications: IHC-p, IF, ELISA
Reactivity: Human, Mouse
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: IRE1alpha/beta Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 102251
UniProt Accession: Human: Q76MJ5; Mouse: Q9Z2E3
Synonyms: ERN2; IRE2; Serine/threonine-protein kinase/endoribonuclease IRE2; Endoplasmic reticulum-to-nucleus signaling 2; Inositol-requiring protein 2; hIRE2p; Ire1-beta; IRE1b
GeneID: Human: 10595; Mouse: 26918
Research Use Only