IRS2 Polyclonal Antibody
Sizes: 20μL, 50μL, 100μL
Catalogue Numbers: BT-AP04651-20, BT-AP04651-50, BT-AP04651-100
Citations, Manuals and MSDS Available upon request.
Background: IRS2 (insulin receptor substrate 2) encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of IRS2 is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Research Areas: Signal Transduction
Target Protein: IRS2
Applications: WB, ELISA
Reactivity: Human
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
Full Product Name: IRS2 Antibody
Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189
Storage: -20°C for 1 year
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration: 1 mg/ml
Molecular Weight (Da): 147180
UniProt Accession: Human: Q9Y4H2; Mouse: P81122
Synonyms: IRS2
GeneID: Human: 8660; Mouse: 384783
Research Use Only