MT3 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-15198-60, E-AB-15198-120, E-AB-15198-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MT3
Target Synonym: GIF; GIFB; GRIF; Growth inhibitory factor; Metallothionein 3 (growth inhibitory factor (neurotrophic)); Metallothionein 3; Metallothionein III; Metallothionein-3; Metallothionein-III; Mt 3; MT III; MT-3; MT-III; MT3; MT3; ZnMT3
Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P25713
Background: Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in micro-organisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. Metallothionein are implicated primarily in metal ion detoxification as they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue. Metallothionein 3, also known as MT-3 or GIFB (growth inhibitory factor), is a 68 amino acid protein that belongs to the type 1 family and Metallothionein superfamily. While highly expressed in astrocytes of the normal human brain, Metallothionein 3 expression is reduced in the brains of patients with Alzheimer disease.
Concentration: 0.5 mg/mL
Immunogen: Recombinant protein of human MT3
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only