Nuclear Receptor NR4A1 (Phospho-Ser351) Rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES14439-50, ES14439-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],
Alternate Name: Nuclear receptor subfamily 4 group A member 1 (Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3)
Source: Rabbit
Applications: WB; ELISA
Dilution: WB 1:500-2000, ELISA (peptide)1:5000-20000
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized pospho peptide derived from human Nuclear Receptor NR4A1 (Phospho-Ser351)
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 77kD
Human Gene ID: 3164
Human SWISS Prot NO: P22736
Subcellular Location: Nucleus. Cytoplasm. Mitochondrion. Nuclear export to the cytoplasm is XPO1-mediated and positively regulated by IFI27 (PubMed:22427340). Translocation to the mitochondrion upon interaction with RXRA and upon the presence of 9-cis retinoic acid (PubMed:17761950).
Research Use Only