Sodium Potassium ATPase alpha-1 (Phospho-Tyr260) Rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES8616-50, ES8616-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],
Alternate Name: Sodium/potassium-transporting ATPase subunit alpha-1 (Na (+)/K (+) ATPase alpha-1 subunit) (EC 3.6.3.9) (Sodium pump subunit alpha-1)
Source: Rabbit
Applications: WB; ELISA; IHC
Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Reactivity: Human; Rat; Mouse
Immunogen: Synthetic peptide from human protein at AA range: 230-290
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 115kD
Human Gene ID: 476
Human SWISS Prot NO: P05023
Subcellular Location: Basolateral cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection, axon. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Research Use Only