SYK (Phospho-Tyr348) Rabbit pAb
Sizes: 50μL, 100μL
Catalogue Numbers: ES8875-50, ES8875-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Alternate Name: Tyrosine-protein kinase SYK (EC 2.7.10.2) (Spleen tyrosine kinase) (p72-Syk)
Source: Rabbit
Applications: WB; ELISA; IHC
Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Reactivity: Human; Mouse; Rat
Immunogen: Synthesized phospho derived from human SYK (Phospho-Tyr348)
Storage and Stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band (KD): 82kD
Human Gene ID: 6850
Human SWISS Prot NO: P43405
Subcellular Location: Cell membrane. Cytoplasm, cytosol.
Research Use Only