Vorsetuzumab ELISA Kit
Size: 96T
Catalogue Number: DW717028-96
Citations, Manuals and MSDS Available upon request.
Stability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Detection Method: Colorimetric
Sample Type: Plasma, Serum
Assay Type: Quantitative
Sensitivity: 0.156 μg/ml
Range: 0.31-5 μg/mL
Recovery: 80-120%
Background: Vorsetuzumab mafodotin, also known as SGN-75, is a novel antibody conjugated with a cytotoxic molecule, auristatin analogue monomethyl auristatin phenylalanine (MMAF). The antibody part of vorsetuzumab mafodotin is a monoclonal antibody targeting CD70, a member of CD70 tumor necrosis factor (TNF) superfamily. Vorsetuzumab mafodotin, developed by Seattle Genetics, has been used in the clinical treatment of Non-Hodgkin's lymphoma and renal cancer. This drug has completed a phase I clinical study in renal cell carcinoma but was discontinued in 2013. There were no reports specifying the reasons for the cessation of development. In 2014, SG had planned to reopen clinical studies related to vorsetuzumab mafodotin.
Shipping: 2-8 ℃
For Research Use Only.