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View abinScience ELISA, antibody, protein collection

Vunakizumab ELISA Kit - DS856078

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Vunakizumab ELISA Kit

Size: 96T

Catalogue Number: DS856078-96

Citations, Manuals and MSDS Available upon request.

Stability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection Method: Colorimetric

Sample Type: Plasma, Serum

Assay Type: Quantitative

Sensitivity: 0.156 μg/ml

Range: 0.31-5 μg/mL

Recovery: 80-120%

Background: Vunakizumab is a recombinant humanized IgGκ monoclonal antibody binds to and neutralises the proinflammatory cytokine interleukin-17A (IL-17A). It was discovered and developed by Jiangsu Hengrui Medicine (China) with the developmental name SHR-1314, for the treatment of autoimmune diseases such as psoriasis, psoriatic arthritis, ankylosing spondylitis, multiple sclerosis and inflammatory arthritis. Atridia Pty. Ltd., which is now a part of Jiangsu Hengrui Medicine, start a phase-I clinical trial in psoriasis (in volunteers) in Australia in August 2016. Atridia completed the phase-I trial in July 2017. A phase-I/II study, which is started from December 2017, is ongoing to assess the safety, tolerability, and pharmacokinetics of SHR-1314 with expanded dose finding in subjects with moderate-to-severe plaque psoriasis.

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