ABCB11 Polyclonal Antibody
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sizes: 50µl, 100µl
Catalogue Numbers: BS79913-50, BS79913-100
Swiss-Prot: O95342
Host: Rabbit
ABCB11 Polyclonal Antibody-BS79913
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Reactivity: Mouse, Rat
Applications: IF/ICC
All Applications: IF/ICC,1:50 - 1:200
Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Specificity: Unmodification
Bioworld Molecular Weight: 146kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunofluorescence analysis of C6 cells using ABCB11 antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of NIH/3T3 cells using ABCB11 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Alternative Name: ABCB11; ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP
Immunogen: A synthetic peptide of human ABCB11(NP_003733.2).
Modification: Unmodified
Conjugate: Unconjugated