ABCC13 Polyclonal Antibody
Catalogue Numbers: BS62443-50, BS62443-100
Sizes: 50µl, 100µl
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.
Swiss-Prot: Q9NSE7
Host: Rabbit
Reactivity: Human
Applications: WB IHC
All Applications: WB:1:500~1:1000 IHC:1:50~1:200
Background: The S-100 protein family consists of a group of calcium-binding proteins that are exclusively expressed in vertebrates and exhibit cell and tissue-specific expression. The expression levels of its members differ in various pathological conditions. The extracellular functions of the S-100 family may include the ability to enhance neurite outgrowth, involvement in inflammation and motility of tumor cells. S-100Z (S100 calcium-binding protein Z) is a 99 amino acid protein that shares 57% and 52% sequence identity with S-100A1 and S-100P, respectively. A dimeric, predominantly α-helical protein, S-100Z contains two EF-hand domains capable of binding calcium ions. Binding of calcium results in conformational changes and exposure of hydrophobic surfaces on the protein. S-100Z interacts with S-100P, and demonstrates highest level of expression in spleen and leukocytes. The S-100Z gene is conserved in chimpanzee, bovine, mouse, rat, chicken and zebrafish, and maps to human chromosome 5q13.3.
Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.
Specificity: ABCC13 polyclonal antibody detects endogenous levels of ABCC13 protein.
Extra Notes: Western blot (WB) analysis of ABCC13 polyclonal antibody at 1:500 dilution
LaneA:HT29 whole cell lysate
Bioworld Molecular Weight: ~ 31 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: ABCC13
Immunogen: Synthetic peptide, corresponding to Human ABCC13.
Conjugate: Unconjugated
Modification: Unmodified