Acetyl-DNMT1-K1127/K1129/K1131/K1133 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS7948-50, BS7948-100
Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P26358
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: IHC, IF/ICC
All Applications: IHC,1:50 - 1:100 | IF/ICC,1:50 - 1:100
Background: This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Acetylated Antibodies
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunofluorescence analysis of C6 cells using Acetyl-DNMT1-K1127/K1129/K1131/K1133 antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Alternative Name: ADCADN; AIM; CXXC9; DNMT; HSN1E; MCMT; m.HsaI; DNMT1
Immunogen: A synthetic acetylated peptide around K1127 & K1129 & K1131 & K1133 of human DNMT1(NP_001124295.1).
Conjugate: Unconjugated
Modification: Unmodified