AChRα5 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS6567-50, BS6567-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P30532
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB
All Applications: WB 1:500 - 1:2000
Background: Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα5, also known as LNCR2 or CHRNA5 (cholinergic receptor, nicotinic, alpha 5), is a 468 amino acid multi-pass membrane protein belonging to the ligand-gated ionic channel family and is involved in the mediation of fast signal transmission at synapses.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: AChRα5 polyclonal antibody detects endogenous levels of AChRα5 protein.
Bioworld Molecular Weight: ~ 53 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot analysis of extracts of mouse brain tissue cell lines, using AChRα5 antibody.
Alternative Name: ACHA5; alpha polypeptide 5; cholinergic receptor; Cholinergic receptor neuronal nicotinic alpha polypeptide 5; Cholinergic receptor nicotinic alpha 5; Cholinergic receptor nicotinic alpha polypeptide 5; CHRNA 5; CHRNA5; LNCR2; NACHRA 5; NACHRA5; Neuronal acetylcholine receptor subunit alpha 5; Neuronal acetylcholine receptor subunit alpha-5; Neuronal nicotinic acetylcholine receptor alpha 5 subunit; Neuronal nicotinic acetylcholine receptor; alpha5 subunit; nicotinic;
Immunogen: Recombinant full length Human AChRα5.
Conjugate: Unconjugated
Modification: Unmodified