AF/LE Purified Anti-Human CD11a Antibody [R7-1] - E-AB-F12110

AF/LE Purified Anti-Human CD11a Antibody [R7-1]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F12110-500, E-AB-F12110-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD11a

Target Synonym: Integrin alpha-L, LFA-1A, CD11A, ITGAL,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Mouse

Species Reactivity: Human

Application: FCM, FA

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Mouse IgG1, κ

Clone No.: R7-1

UNIProt ID: P20701

Background: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F097930

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 3683

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only