AF/LE Purified Anti-Mouse CD209b Antibody [22D1] - E-AB-F10220

AF/LE Purified Anti-Mouse CD209b Antibody [22D1]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F10220-500, E-AB-F10220-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD209b

Target Synonym: CD209 antigen-like protein B, Cd209b, DC-SIGN-related protein 1, DC-SIGNR1, OtB7, CD209, Cd209b,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Armenian Hamster

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Armenian Hamster IgG

Clone No.: 22D1

UNIProt ID: Q8CJ91

Background: CD209B, also known as SIGN-R1, is a mouse C-type lectin receptor predominantly expressed on macrophages in the spleen marginal zone and lymph nodes medulla. CD209B is a mouse homolog of human CD209/DC-SIGN and is involved in innate immune response. CD209B mediates the recognition and uptake of pathogen products, such as lipopolysaccharides (LPS), pneumococcal polysaccharides, and dextrans. CD209B has been demonstrated to facilitate the clearance of encapsulated pneumococcus by directly binding to C1q and activating complement through an immunoglobulin independent pathway.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098530

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 69165

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only