AF/LE Purified Anti-Mouse CD8a Antibody [53-6.7] - E-AB-F11040

AF/LE Purified Anti-Mouse CD8a Antibody [53-6.7]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F11040-500, E-AB-F11040-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD8a

Target Synonym: T-cell surface glycoprotein CD8 alpha chain, CD8A, T-lymphocyte differentiation antigen T8/Leu-2, MAL,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Rat

Species Reactivity: Mouse

Application: FCM,Block,Depletion

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Rat IgG2a, κ

Clone No.: 53-6.7

UNIProt ID: P01731

Background: CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098330

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 12525

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only