AF/LE Purified Anti-Mouse TCR γ/δ Antibody [UC7-13D5] - E-AB-F11240

AF/LE Purified Anti-Mouse TCR γ/δ Antibody [UC7-13D5]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F11240-500, E-AB-F11240-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: TCR γ/δ

Target Synonym: TCR-γ/δ, γ/δ TCR,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Armenian Hamster

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Armenian Hamster IgG

Clone No.: UC7-13D5

Background: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098530

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 110066110067

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only