APC Anti-Human CD45RO Antibody [UCHL1] - E-AB-F1139E

APC Anti-Human CD45RO Antibody [UCHL1]

Sizes: 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1139E-100, E-AB-F1139E-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD45RO

Conjugation: APC

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Mouse IgG2a, κ

Clone No.: UCHL1

Background: CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09802E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Gene ID: 5788

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only