APC Anti-Human CD61 Antibody [VI-PL2]
Sizes: 100 Tests, 100 Tests×2
Catalogue Numbers: E-AB-F1166E-100, E-AB-F1166E-100×2
Citations, Manuals and MSDS Available upon request.
Abbreviation: CD61
Target Synonym: GP3A, GPIIIa, ITGB3, Integrin beta-3,
Conjugation: APC
Host: Mouse
Species Reactivity: Human
Application: FCM
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Isotype: Mouse IgG1, κ
Clone No.: VI-PL2
UNIProt ID: P05106
Background: CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
Concentration: 5 μL/Test
Control Catalogue Number: E-AB-F09792E
Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Gene ID: 3690
Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.
Shipping: Ice bag
Research Use Only