APC Anti-Human CD80 Antibody [2D10] - E-AB-F1232E

APC Anti-Human CD80 Antibody [2D10]

Sizes: 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1232E-100, E-AB-F1232E-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD80

Target Synonym: T-lymphocyte activation antigen CD80, B7-1, B7, BB1,

Conjugation: APC

Host: Mouse

Species Reactivity: Human

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Mouse IgG1, κ

Clone No.: 2D10

UNIProt ID: P33681

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09792E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Gene ID: 941

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only