APC Anti-Mouse F4/80 Antibody [CI:A3-1] - E-AB-F0995UE

APC Anti-Mouse F4/80 Antibody [CI:A3-1]

Size: 100μg

Catalogue Number: E-AB-F0995UE-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: F4/80

Target Synonym: Adhesion G protein-coupled receptor E1, Adgre1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, Adgre1, Emr1, Gpf480,

Conjugation: APC

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2b, κ

Clone No.: CI:A3-1

UNIProt ID: Q61549

Background: F4/80 is a 160 kD glycoprotein. It is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80, also known as EMR1 or Ly71, has been widely used as a murine macrophage marker, which is expressed on the majority of tissue macrophages including peritoneal macrophages, macrophages in lung, gut, thymus and red pulp of spleen (but not on the macrophages located in T cell areas of the spleen, lymph node and Peyer's patch), Kuffer cells, Langerhans cells, and bone marrow stromal cells. F4/80 has also been shown on a subset of dendritic cells. The biological ligand of F4/80 has not been identified, but it has been reported that F4/80 is required for induction of CD8+ T cells-mediated peripheral tolerance.

Concentration: 0.2 mg/mL

Control Catalogue Number: E-AB-F09843E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 13733

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag