APC Anti-Mouse IL-10 Antibody [JES5-16E3] - E-AB-F1197E

APC Anti-Mouse IL-10 Antibody [JES5-16E3]

Sizes: 100 Tests, 100 Tests×2

Catalogue Numbers: E-AB-F1197E-100, E-AB-F1197E-100×2

Citations, Manuals and MSDS Available upon request.

Abbreviation: IL-10

Target Synonym: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF,

Conjugation: APC

Host: Rat

Species Reactivity: Mouse

Application: ICFCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Isotype: Rat IgG2b, κ

Clone No.: JES5-16E3

UNIProt ID: P18893

Background: L-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. IL-10 inhibits IFN-γ, TNF-β, and IL-2 production by Th1 clones, inhibits macrophage-mediated IL-1, IL-6, and TNF-α synthesis, suppresses the delayed type hypersensitivity response, stimulates Th2 cell response (which results in elevated antibody production), and promotes mast cell proliferation in combination with IL-4.

Concentration: 5 μL/Test

Control Catalogue Number: E-AB-F09842E

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Gene ID: 16153

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag

Research Use Only