APEH Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-12756-60, E-AB-12756-120, E-AB-12756-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: APEH
Target Synonym: AARE; ACPH; ACPH; Acyl peptide hydrolase; Acyl-peptide hydrolase; Acylamino acid releasing enzyme; Acylamino-acid-releasing enzyme; Acylaminoacyl peptidase; Acylaminoacyl-peptidase; APEH; APH; N acylaminoacyl peptide hydrolase; OPH; Oxidized protein hydrolase
Research Areas: Cancer, Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P13798
Background: This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Concentration: 0.3 mg/mL
Immunogen: Synthetic peptide of human APEH
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Calculated MW: 81kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only