ITGB2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-15140-60, E-AB-15140-120, E-AB-15140-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: ITGB2
Target Synonym: 95 subunit beta; Beta 2 (antigen CD18 (p95); CD 18; CD18; Cell surface adhesion glycoprotein LFA 1/CR3/P150; 959 beta subunit precursor); Cell surface adhesion glycoproteins LFA 1/CR3/p150; 95 subunit beta; Cell surface adhesion glycoproteins LFA-1/CR3/p150; Complement component 3 receptor 3 and 4 subunit; Complement receptor C3 beta subunit; Complement receptor C3 subunit beta; Integrin beta 2; Integrin beta chain beta 2; Integrin beta-2 (ITGB2); Integrin beta-2; Integrin; beta 2 (complement component 3 receptor 3 and 4 subunit); ITB2; ITGB2; LAD; LCAMB; Leukocyte associated antigens CD18/11A; CD18/11B; CD18/11C; Leukocyte cell adhesion molecule CD18; LFA 1; LFA1; Lymphocyte function associated antigen 1 (LFA1); Lymphocyte function associated antigen 1; MAC 1; MAC1; Macrophage antigen 1 (mac1) beta; MF17; MFI7; OTTHUMP00000115278; OTTHUMP00000115279; OTTHUMP00000115280; OTTHUMP00000115281; OTTHUMP00000115282
Research Areas: Cancer, Immunology, Signal Transduction, Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P05107
Background: The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine witHuman, Mouseultiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene.
Concentration: 0.3 mg/mL
Immunogen: Recombinant protein of human ITGB2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:25-1:100
Calculated MW: 85kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only