ITGB7 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16525-60, E-AB-16525-120, E-AB-16525-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: ITGB7
Target Synonym: Gut homing receptor beta subunit; Integrin beta 7 subunit; Integrin beta-7; Integrin beta-P; Integrin; beta 7; ITB7; ITB7; Itgb7; Ly69; M290 IEL antigen
Research Areas: Cancer, Signal transduction, Stem cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P26010
Background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Concentration: 0.7 mg/mL
Immunogen: Synthetic peptide of human ITGB7
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:100-1:300
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only