KCNA1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-66980-60, E-AB-66980-120, E-AB-66980-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: KCNA1
Target Synonym: KCNA1; AEMK; EA1; HBK1; HUK1; KV1.1; MBK1; MK1; RBK1
Research Areas: Cancer, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse, Rat
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q09470
Background: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human KCNA1 (NP_000208.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only