KCNA5 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-14174-60, E-AB-14174-120, E-AB-14174-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: KCNA5
Target Synonym: ATFB7; cardiac potassium channel; HCK1; HK2; HPCN1; insulinoma and islet potassium channel; KCNA5; KCNA5; KV1.5; PCN1; potassium channel 1; Potassium channel; insulinoma and islet cell; Potassium channel; voltage-gated; shaker-related subfamily; member 5; Potassium voltage gated channel subfamily A member 5; Potassium voltage-gated channel subfamily A member 5; Voltage-gated potassium channel HK2; voltage-gated potassium channel protein Kv1.5; Voltage-gated potassium channel subunit Kv1.5
Research Areas: Cancer, Cardiovascular, Metabolism, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P22460
Background: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7).
Concentration: 0.4 mg/mL
Immunogen: Recombinant protein of human KCNA5
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 67kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only