KCNQ4 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16544-60, E-AB-16544-120, E-AB-16544-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: KCNQ4
Target Synonym: DFNA 2; DFNA2; KCNQ 4; Kcnq4; KCNQ4; KQT like 4; KQT-like 4; KV7.4; Potassium channel KQT like 4; Potassium channel subunit alpha KvLQT4; Potassium voltage gated channel KQT like protein 4; Potassium voltage gated channel KQT like subfamily member 4; Potassium voltage gated channel subfamily KQT member 4; Potassium voltage-gated channel subfamily KQT member 4; Voltage gated potassium channel subunit Kv7.4; Voltage-gated potassium channel subunit Kv7.4
Research Areas: Cancer, Neuroscience
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P56696
Background: The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
Concentration: 0.9 mg/mL
Immunogen: Synthetic peptide of human KCNQ4
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:200-1:1000, IHC 1:50-1:200
Calculated MW: 77kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only