(KO Validated) Bcl-2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-93314-60, E-AB-93314-120, E-AB-93314-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: Bcl-2
Target Synonym: BCL2; Bcl-2; PPP1R50; apoptosis regulator Bcl-2
Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P10415
Background: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human Bcl-2
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200
Calculated MW: 22kDa/26kDa
Observed MW: 26KDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only