(KO Validated) MSH2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-92378-60, E-AB-92378-120, E-AB-92378-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MSH2
Target Synonym: MSH2; COCA1; FCC1; HNPCC; HNPCC1; LCFS2; mutS homolog 2
Research Areas: Cancer, Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB, IP
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P43246
Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MSH2
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IP 1:50-1:200
Calculated MW: 97kDa/104kDa
Observed MW: 105KDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only