Lgals3 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-40655-50, E-AB-40655-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Lgals3
Target Synonym: LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; CBP 35; Galactose-specific lectin 3; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen
Research Areas: Neuroscience, Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, mouse, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P08699
Background: Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
Concentration: 1.7mg/mL
Immunogen: Recombinant Rat Lgals3 protein expressed by E.coli
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Purification Method: Antigen Affinity Purification
Dilution: WB:1:250-1:500
Calculated MW: 26kDa
Observed MW: 28kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only