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LMNB2 Polyclonal Antibody - E-AB-61994

LMNB2 Polyclonal Antibody - E-AB-61994

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LMNB2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-61994-60, E-AB-61994-120, E-AB-61994-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: LMNB2

Target Synonym: LMNB2; EPM9; LAMB2; LMN2; lamin-B2

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal Transduction, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q03252

Background: This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human LMNB2 (NP_116126.3).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200 IF 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only