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LRIG1 Polyclonal Antibody - E-AB-12544

LRIG1 Polyclonal Antibody - E-AB-12544

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LRIG1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-12544-60, E-AB-12544-120, E-AB-12544-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: LRIG1

Target Synonym: Leucine rich repeat protein; Leucine rich repeat protein LRIG1; leucine rich repeats and immunoglobulin like domains 1; Leucine-rich repeats and immunoglobulin-like domains protein 1; leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1; LIG 1; LIG-1; LIG1; Lrig1; LRIG1; Ortholog of mouse integral membrane glycoprotein LIG 1

Research Areas: Cancer

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96JA1

Background: Leucine-rich repeats and immunoglobulin-like domains protein 1is aproteinthat in humans is encoded by theLRIG1gene.It encodes atransmembrane proteinthat has been shown to interact with receptor tyrosine kinases of theEGFR-family, METandRET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.

Concentration: 1 mg/mL

Immunogen: Synthetic peptide of human LRIG1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only