LXN Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-10437-60, E-AB-10437-120, E-AB-10437-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: LXN
Target Synonym: ECI; Endogenous carboxypeptidase inhibitor; Latexin; Latexin protein; LXN; LXN; MUM; Protein MUM; TCI; Tissue carboxypeptidase inhibitor
Research Areas: Cancer, Cell Biology, Immunology, Stem Cells, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9BS40
Background: Latexin, also designated endogenous carboxypeptidase inhibitor (ECI) or tissue carboxypeptidase inhibitor (TCI), belongs to the protease inhibitor I47 family of proteins. Latexin acts as a non-competitive, reversible inhibitor for metallocarboxypeptidases (MCPs), including CPA1, CPA2 and CPA4. It is a cytoplasmic protein that is highly expressed in heart, prostate, pancreas, ovary, kidney, brain and colon. Latexin consists of two topologically equivalent subdomains that bind to MCPs with low specificity, which gives it with the flexibility to inhibit all vertebrate A/B MCPs.
Concentration: 0.6 mg/mL
Immunogen: Recombinant protein of human LXN
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: WB 1:1000-1:5000
Calculated MW: 26kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only