MAGEL2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-13399-60, E-AB-13399-120, E-AB-13399-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MAGEL2
Target Synonym: Mage-l2; MAGE-like 2; MAGE-like protein 2; MAGEL2; melanoma antigen-like gene 2; NDNL1; Necdin like protein 1; necdin-like 1; nM15; ns7; Protein nM15; PWLS
Research Areas: Cancer, Immunology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9UJ55
Background: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Concentration: 0.8 mg/mL
Immunogen: Synthetic peptide of human MAGEL2
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only