MCM7 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-40231-60, E-AB-40231-120, E-AB-40231-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MCM7
Target Synonym: CDABP0042; CDC 47; CDC47; CDC47 homolog; Cdc47; S. cerevisiae; homolog of; DNA replication licensing factor MCM7; Homolog of S. cerevisiae Cdc47; MCM 2; MCM 7; MCM2; MCM2; formerly; Mcm7; MCM7 minichromosome maintenance deficient 7; MCM7_HUMAN; Minichromosome Maintainence 7; Minichromosome maintainence; S. cerevisiae; homolog of; Minichromosome maintenance complex component 7; Minichromosome maintenance deficient 7; Minichromosome maintenance protein 7; P1.1 MCM3; P1.1-MCM3; P1CDC47; P85MCM; PNAS 146; PNAS146; PPP1R104; Protein phosphatase 1; regulatory subunit 104
Research Areas: Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P33993
Background: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Concentration: 2 mg/mL
Immunogen: Recombinant Human DNA replication licensing factor MCM7 protien
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only