MDFI Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-18801-60, E-AB-18801-120, E-AB-18801-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MDFI
Target Synonym: I MF; I mfa; Inhibitor of MyoD family a; Mdfi; MDFI; MyoD family inhibitor; Myogenic repressor I-mf; OTTHUMP00000016375; OTTHUMP00000016376; OTTHUMP00000196103; OTTHUMP00000196414; OTTHUMP00000196415
Research Areas: Epigenetics and Nuclear Signaling, Developmental Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB, IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q99750
Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.MDFI (MyoD Family Inhibitor) is a Protein Coding gene. GO annotations related to this gene include transcription factor binding. An important paralog of this gene is MDFIC.
Concentration: 0.96 mg/mL
Immunogen: Fusion protein of human MDFI
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
Calculated MW: 25 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only