MEP1B Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-65731-60, E-AB-65731-120, E-AB-65731-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MEP1B
Target Synonym: MEP1B
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q16820
Background: Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MEP1B (NP_005916.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:1000
Calculated MW: 79kDa
Observed MW: 105kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only