METTL7A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-52354-60, E-AB-52354-120, E-AB-52354-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: METTL7A
Target Synonym: AAM B; AAMB; DKFZP586A0522; MET7A; Methyltransferase like 7A; Methyltransferase-like protein 7A; METTL 7A; METTL7A; METTL7A methlytransferase like 7A; Protein AAM-B; Protein AAMB
Research Areas: Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9H8H3
Background: METTL7A (methyltransferase like 7A), also known as AAM-B, is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1, 100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.
Concentration: 0.6 mg/mL
Immunogen: Fusion protein of human METTL7A
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only