MICU1 Monoclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-22114-60, E-AB-22114-120, E-AB-22114-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MICU1
Target Synonym: Allergen Hom s 4; ara CALC; atopy related autoantigen; atopy related autoantigen CALC; Atopy-related autoantigen CALC; CALC; calcium binding atopy related autoantigen 1; Calcium uptake protein 1; calcium uptake protein 1; mitochondrial; Calcium-binding atopy-related autoantigen 1; CBARA1; EFHA3; FLJ12684; MICU1; MICU1; mitochondrial; mitochondrial calcium uptake 1; MPXPS
Research Areas: Cancer, Metabolism, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-p, IF
Isotype: IgG
Clonality: Monoclonal
Clone No.: Clone:4E7
UNIProt ID: Q9BPX6
Background: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
MICU1 (Mitochondrial Calcium Uptake 1) is a Protein Coding gene. Diseases associated with MICU1 include Myopathy With Extrapyramidal Signs and Fish Allergy. Among its related pathways are Ca, cAMP and Lipid Signaling. GO annotations related to this gene include calcium ion binding and protein heterodimerization activity. An important paralog of this gene is MICU3.
Concentration: 1 mg/mL
Immunogen: Recombinant Protein
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:200, IF 1:100-1:300
Observed MW: 55kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only