MRGPRX1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16618-60, E-AB-16618-120, E-AB-16618-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MRGPRX1
Target Synonym: GPCR; MAS related gene MRGX1; MAS related GPR member X1; MRGPRX1; MRGX1; SNSR4
Research Areas: Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q96LB2
Background: MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.
Concentration: 0.5 mg/mL
Immunogen: Synthetic peptide of human MRGPRX1
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only