MTHFD2 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-65766-60, E-AB-65766-120, E-AB-65766-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MTHFD2
Target Synonym: MTHFD2; NMDMC
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P13995
Background: This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human MTHFD2 (NP_006627.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only