MutS Protein Homolog 2 (MSH2) Monoclonal Antibody
Sizes: 100μL, 200μL
Catalogue Numbers: PA6750-100, PA6750-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: MutS Protein Homolog 2(MSH2)
Target Synonym: MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human
Application: IHC-P
Clonality: Monoclonal
Clone No.: YN01126m
UNIProt ID: P43246
Background: DNA mismatch repair (MMR) system is composed of enzyme molecules that specifically repair DNA base mismatch. The existence of this system can ensure the integrity and stability of genetic material, avoid the mutation of genetic material, and ensure the high fidelity of DNA replication. It is composed of hMLH1, hMSH2, hpms1, hPMS2 and other genes. HMSH2 is located in human chromosome 2p21-22, encoding a protein composed of 934 aa. The mutation of hMSH2 gene occurs in sporadic colorectal cancer. The mutation of microsatellite hMSH2 gene is related to 50% of familial and non-familial polyposis colorectal cancer (HNPCC).
The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.
Shipping: Ice bag
Research Use Only