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NCOR1 Polyclonal Antibody - E-AB-61490

NCOR1 Polyclonal Antibody - E-AB-61490

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NCOR1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-61490-60, E-AB-61490-120, E-AB-61490-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NCOR1

Target Synonym: NCOR1; N-CoR; N-CoR1; PPP1R109; TRAC1; hN-CoR

Research Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IF

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O75376

Background: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human NCOR1 (NP_006302.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: IF 1:50-1:100

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only